Article
Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations.
Molecular nutrition & food research - 1 Feb 2007
Fisher Eva, Nitz Inke, Gieger Christian, Grallert Harald, Gohlke Henning, Lindner Inka, Dahm Stefan, Boeing Heiner, Burwinkel Barbara, Rathmann Wolfgang, Wichmann H-Erich, Schrezenmeir Jürgen, Illig Thomas, Döring Frank
Abstract excerpt
The human acyl-CoA-binding protein (ACBP) is a potential candidate gene of type 2 diabetes (T2D), since it plays a central role in determining the intracellular concentration of activated fatty acids which contribute to insulin resistance. The aim of our study was to evaluate whether single nucleotide polymorphisms (SNPs) of the ACBP gene are associated with risk of T2D. Genotyping of eight SNPs (rs2084202,...
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