Article
The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents.
Obesity (Silver Spring, Md.) - 1 Sept 2009
Nordquist Niklas, Göktürk Camilla, Comasco Erika, Eensoo Diva, Merenäkk Liis, Veidebaum Toomas, Oreland Lars, Harro Jaanus
Abstract excerpt
Insulin resistance and central adiposity are strong risk indicators for type 2 diabetes and coronary heart disease. An important role for adipose tissue in the etiology and progression of these conditions has recently become more evident. A transcription factor, TFAP2B, has been shown to participate in the regulation of adipocyte metabolism, by facilitating glucose uptake and lipid accumulation, while...
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