Article
Distribution of glutathione S-transferase M1, P1 and T1 genotypes in different age-groups of Finns without diagnosed cancer.
Cancer detection and prevention - 1 Jan 2006
Voho Anu, Impivaara Olli, Järvisalo Jorma, Metsola Katja, Vainio Harri, Hirvonen Ari
Abstract excerpt
BACKGROUND: Xenobiotic metabolizing enzymes (XMEs) are important detoxifiers of hazardous environmental agents, and their polymorphisms may therefore modify the risk of environmentally induced cancers. Consequently, the XME polymorphisms have been extensively studied in this context during recent years. Particular attention has been given to the polymorphisms of glutathione S-transferase (GST) M1, P1 and T1...
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