Article
Polymorphisms of glutathione-S-transferase M1, T1, P1 and the risk of prostate cancer: a case-control study.
Journal of experimental & clinical cancer research : CR - 5 Mar 2009
Sivonová Monika, Waczulíková Iveta, Dobrota Dusan, Matáková Tatiana, Hatok Jozef, Racay Peter, Kliment Ján
Abstract excerpt
BACKGROUND: It has been suggested that polymorphisms in glutathione-S-transferases (GST) could predispose to prostate cancer through a heritable deficiency in detoxification pathways for environmental carcinogens. Yet, studies linking GST polymorphism and prostate cancer have so far failed to unambiguously establish this relation in patients. A retrospective study on healthy, unrelated subjects was conducted in...
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