Article
Molecular mutation profile of pfcrt in Plasmodium falciparum isolates imported from Africa in Henan province.
Malaria journal - 10 May 2016
Zhou Rui-Min, Zhang Hong-Wei, Yang Cheng-Yun, Liu Ying, Zhao Yu-Ling, Li Su-Hua, Qian Dan, Xu Bian-Li
Abstract excerpt
BACKGROUND: Anti-malarial drug resistance is a primary public health problem. Haplotypes of pfcrt gene have been implicated to be molecular markers of chloroquine (CQ) resistance. This study aims to explore the prevalence of polymorphisms in pfcrt in Plasmodium falciparum-infected patients imported from Africa in Henan province. METHODS: Blood samples were collected from 502 patients who were infected with P....
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