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Article

Association of alpha4beta2 nicotinic receptor and heavy smoking in schizophrenia.

Journal of psychiatry & neuroscience : JPN - 1 Nov 2007

Voineskos Sophocles, De Luca Vincenzo, Mensah Albert, Vincent John B, Potapova Natalia, Kennedy James L

Abstract excerpt

INTRODUCTION: Previously we suggested that the CHRNA7 polymorphism in nicotinic receptor genes, in particular the D15S1360 in CHRNA7, is associated with smoking in schizophrenia. Schizophrenia patients are usually heavy smokers. In this study we hypothesized that high-affinity nicotinic receptors are associated with smoking in such patients. OBJECTIVE: To investigate the role of alpha4 (Ch 20) and beta2 (Ch 1)...

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Share to CHRNA4 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 18043764
PMCID: PMC2077346

Genes

CHRNA4
CHRNA7
CHRNB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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