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Article

Small heat shock proteins inhibit amyloid-beta protein aggregation and cerebrovascular amyloid-beta protein toxicity.

Brain research - 17 May 2006

Wilhelmus Micha M M, Boelens Wilbert C, Otte-Höller Irene, Kamps Bram, de Waal Robert M W, Verbeek Marcel M

Abstract excerpt

Small heat shock proteins Hsp20 and HspB2/B3 co-localize with Abeta deposition in senile plaques and cerebral amyloid angiopathy in Alzheimer's disease brains, respectively. It was the aim of our study to investigate if these and other sHsps bind to wild-type Abeta1-42 or the more toxic Abeta1-40...

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Share to Amyloid beta-Peptides
Share to Cerebral Amyloid Angiopathy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16635482
DOI: 10.1016/j.brainres.2006.03.058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16635482-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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