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Article

Energy expenditure, body composition and insulin response to glucose in male twins discordant for the Trp64Arg polymorphism of the beta3-adrenergic receptor gene.

Diabetes, obesity & metabolism - 1 May 2006

Højlund K, Christiansen C, Bjørnsbo K S, Poulsen P, Bathum L, Henriksen J E, Lammert O, Beck-Nielsen H

Abstract excerpt

AIM: The tryptophan to arginine change in position 64 (Trp64Arg) polymorphism of the beta3-adrenergic receptor (beta3AR) gene has been associated with an increased prevalence of obesity, insulin resistance and type 2 diabetes. In this, decreased rates of energy expenditure and impaired insulin secretion could play a role. METHODS: In 10 male twin pairs discordant for the Trp64Arg polymorphism, we examined insulin...

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Identifiers

PMID: 16634992
DOI: 10.1111/j.1463-1326.2005.00509.x

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