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Article

The Trp64Arg mutation of the adrenergic beta-3 receptor gene impairs insulin secretion: a twin study.

Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 1999

Christiansen C, Poulsen P, Beck-Nielsen H

Abstract excerpt

AIMS: The physiological role of the adrenergic beta-3 receptor is poorly understood in man but the Trp64Arg mutation of the receptor gene has been related to the insulin resistance syndrome, an earlier onset of diabetes and rapid weight gain. This study set out to examine the effects of the mutation on glycaemic responses after an oral glucose tolerance test. METHODS: A standard oral glucose tolerance test (75 g...

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Source

Identifiers

PMID: 10547210
DOI: 10.1046/j.1464-5491.1999.00130.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Trp64Arg mutation of the adrenergic beta-3 receptor gene impairs insulin secretion: a twin study.PMID 10547210Read ↗

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