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Beta 3-adrenergic receptor gene polymorphism and type 2 diabetes in a Caucasian population.

Diabetes, obesity & metabolism - 1 Feb 2001

Oeveren van-Dybicz A M, Vonkeman H E, Bon M A, van den Bergh F A, Vermes I

Abstract excerpt

AIM: The beta 3-adrenergic receptor (beta 3-AR) is suspected to play a key role in the regulation of energy balance by increasing lipolysis and thermogenesis. A mutation in the beta 3-AR gene (Trp64Arg) has been associated with the capacity of weight gain and with early onset of noninsulin dependent diabetes mellitus (type 2 diabetes). In this study we investigated the prevalence of the two beta 3-AR alleles in a...

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Source

Identifiers

PMID: 11213599
DOI: 10.1046/j.1463-1326.2001.00121.x

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Beta 3-adrenergic receptor gene polymorphism and type 2 diabetes in a Caucasian population.PMID 11213599Read ↗

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