Article
Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people.
Molecular genetics and metabolism - 1 May 2008
Gjesing A P, Andersen G, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O
Abstract excerpt
AIM/HYPOTHESIS: The functional variant Trp64Arg in the beta(3)-adrenergic receptor has previously been examined for association with obesity and insulin resistance with ambiguous results. For further evaluation the present study examined the impact of the Trp64Arg variant on the pathogenesis of type 2 diabetes and obesity in a relatively large, homogenous study population. METHODS: The Trp64Arg polymorphism was...
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