Article
Obesity-related phenotypes and the beta3-adrenoceptor gene variant in postmenopausal women.
Diabetes - 1 Jul 1999
Tchernof A, Starling R D, Walston J D, Shuldiner A R, Dvorak R V, Silver K, Matthews D E, Poehlman E T
Abstract excerpt
We examined the hypothesis that postmenopausal women with the beta3-adrenoceptor gene variant (Trp64Arg) have reduced total daily energy expenditure (TEE), altered free fatty acid kinetics, and increased intra-abdominal fat. A secondary objective was to examine whether the obese state masks the effect of the variant on resting metabolic rate (RMR). There were 23 obese heterozygous women with the genetic variant...
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