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Article

Cystic fibrosis transmembrane conductance regulator gene polymorphisms in patients with primary sclerosing cholangitis.

Journal of hepatology - 1 Jan 2009

Henckaerts Liesbet, Jaspers Martine, Van Steenbergen Werner, Vliegen Liesbet, Fevery Johan, Nuytten Hilde, Roskams Tania, Rutgeerts Paul, Cassiman Jean-Jacques, Vermeire Séverine, Cuppens Harry

Abstract excerpt

BACKGROUND/AIMS: Primary sclerosing cholangitis (PSC) is a progressive cholestatic disease commonly associated with inflammatory bowel disease (IBD) and characterized by fibrosing inflammatory destruction of bile ducts. The histological features in the liver of PSC patients are similar to those observed in cystic fibrosis (CF). Our aim was to study whether variants in the CFTR gene are associated with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18992954
DOI: 10.1016/j.jhep.2008.07.033

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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