Article
Transduction with a fiber-modified adenoviral vector is superior to non-viral nucleofection for expressing tumor-associated Ag mucin-1 in human DC.
Cytotherapy - 1 Jan 2006
van Leeuwen E B M, Cloosen S, Senden-Gijsbers B L M G, Germeraad W T V, Bos G M J
Abstract excerpt
BACKGROUND: DC-presenting tumor Ag are currently being developed to be used as a vaccine in human cancer immunotherapy. To increase the chances for successful therapy it is important to deliver full-length tumor Ag instead of loading single peptides. Methodologically, several recombinant DNA deli...
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