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Article

Effects of adenoviral gene transfer of mutated IkappaBalpha, a novel inhibitor of NF-kappaB, on human monocyte-derived dendritic cells.

Acta pharmacologica Sinica - 1 May 2006

Zhou Lin-Fu, Zhang Ming-Shun, Yin Kai-Sheng, Ji Yong, Xie Wei-Ping, Cui Xue-Fan, Ji Xiao-Hui

Abstract excerpt

AIM: To investigate the effects of adenoviral gene transfer of IkappaBalpha mutant (IkappaBalphaM), a novel inhibitor of nuclear factor kappaB (NF-kappaB), on apoptosis, phenotype and function of human monocyte-derived dendritic cells (DC). METHODS: Monocytes, cocultured with granulocyte/macrophage colony-stimulating factor (GM-CSF; 900 ng/mL) and interleukin (IL)-4 (300 ng/mL) for 5 d, followed by stimulation...

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PMID: 16626517
DOI: 10.1111/j.1745-7254.2006.00310.x

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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