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Article

Mutations of the surface protein of hepatitis B virus.

Antiviral research - 1 Oct 2003

Zuckerman Jane N, Zuckerman Arie J

Abstract excerpt

Neutralizing antibodies induced by immunization against hepatitis B infection are targeted to the conformational epitopes of the common a determinant of the surface antigen. However, amino acid substitutions within this region of the surface protein of the virus, particularly in the region of amino acid 137-147 allow replication of hepatitis B virus in vaccinated subjects, since antibodies induced by current...

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Identifiers

PMID: 14638401
DOI: 10.1016/j.antiviral.2003.08.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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