Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-1β-Specific Up-Regulation of Neutrophil Gelatinase-Associated Lipocalin Is Controlled by IκB-ζ

1 May 2006

Abstract excerpt

Neutrophil gelatinase-associated lipocalin (NGAL) is a siderophore-binding protein that exerts a bacteriostatic effect by sequestering iron. Strong induction of NGAL synthesis has been observed in inflamed epithelium of the lungs and colon. Expression of NGAL is up-regulated in the lung epithelial cell line A549 by IL-1beta, but not by TNF-alpha, despite an induction of NF-kappaB binding to the NGAL promoter by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Kidney Injury Research
Share to Immune Response and Inflammation
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16622025
DOI: 10.4049/jimmunol.176.9.5559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

IL-1β-Specific Up-Regulation of Neutrophil Gelatinase-Associated Lipocalin Is Controlled by IκB-ζPMID 16622025Read ↗

The IκB/NF-κB system: a key determinant of mucosal inflammation and protectionSemantic proximity Read ↗

A Novel Member of the IκB Family, Human IκB-ζ, Inhibits Transactivation of p65 and Its DNA BindingSemantic proximity Read ↗

The liver-enriched inhibitory protein isoform of CCAAT/enhancer-binding protein beta, but not nuclear factor-kappaB, mediates the transcriptional inhibition of beta-casein by tumor necrosis factor-alpha.Semantic proximity Read ↗

Human tear lipocalin exhibits antimicrobial activity by scavenging microbial siderophores.Semantic proximity Read ↗

Cellular and molecular mechanisms that mediate basal and tumour necrosis factor-alpha-induced regulation of myosin light chain kinase gene activity.Semantic proximity Read ↗

Human breast milk suppresses the transcriptional regulation of IL-1β-induced NF-κB signaling in human intestinal cellsSemantic proximity Read ↗

Myeloid transcription factor C/EBPepsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils.Semantic proximity Read ↗

A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation.Semantic proximity Read ↗

Pseudomonas aeruginosa- and IL-1beta-mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1.Semantic proximity Read ↗

NF-κB Mediates Up-regulation of CFTR Gene Expression in Calu-3 Cells by Interleukin-1βSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.