Article
Myeloid transcription factor C/EBPepsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils.
Blood - 1 Nov 1999
Verbeek W, Lekstrom-Himes J, Park D J, Dang P M, Vuong P T, Kawano S, Babior B M, Xanthopoulos K, Koeffler H P
Abstract excerpt
Targeted mutation of the myeloid transcription factor C/EBPepsilon in mice results in gram-negative septic death at 3 to 5 months of age. This study defines the underlying molecular defects in their terminal granulocytic differentiation. The mRNA for the precursor protein of the cathelin-related...
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