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Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors

4 Feb 2014

Abstract excerpt

Fetal testis is a major target of endocrine disruptors (EDs). During the last 20 years, we have developed an organotypic culture system that maintains the function of the different fetal testis cell types and have used this approach as a toxicological test to evaluate the effects of various compounds on gametogenesis and steroidogenesis in rat, mouse and human testes. We named this test rat, mouse and human fetal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24497529
DOI: 10.1530/rep-13-0497

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