Article
Influence of GSTM1, GSTT1, GSTP1, NAT1, NAT2, EPHX1, MTR and MTHFR polymorphism on chromosomal aberration frequencies in human lymphocytes.
Carcinogenesis - 1 Mar 2011
Skjelbred Camilla Furu, Svendsen Marit, Haugan Vera, Eek Anette Kildal, Clausen Kjell Oskar, Kure Elin H, Tuimala Jarno T, Svendsen Martin Veel, Norppa Hannu, Hansteen Inger-Lise
Abstract excerpt
We have studied the influence of genetic polymorphisms in the xenobiotic-metabolizing genes GSTM1, GSTP1, GSTT1, EPHX1, NAT1 and NAT2 and the folate-metabolizing genes MTR and MTHFR on the frequencies of cells with chromosomal aberrations (CAs) in peripheral lymphocytes of Norwegian men. Log-linear Poisson regression models were applied on 357 subjects of whom data on all the polymorphisms examined were...
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