Micronuclei in blood lymphocytes and genetic polymorphism for GSTM1, GSTT1 and NAT2 in pesticide-exposed greenhouse workers.

doi:10.1016/s1383-5718(99)00051-0

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Article

Micronuclei in blood lymphocytes and genetic polymorphism for GSTM1, GSTT1 and NAT2 in pesticide-exposed greenhouse workers.

Mutation research - 17 May 1999

Falck G C, Hirvonen A, Scarpato R, Saarikoski S T, Migliore L, Norppa H

Abstract excerpt

The frequency of micronuclei (MN) in cultured peripheral lymphocytes was used as a biomarker of genotoxic effects in 34 Italian pesticide-exposed greenhouse workers and 33 unexposed referents matched with the exposed workers for age and smoking habits. The possible influence of the genetic polymorphisms of xenobiotic metabolizing enzymes glutathione S-transferase M1 (GSTM1), T1 (GSTT1), and N-acetyltransferase 2...

Topics

Acetyltransferases
Adult
Age Factors
Agriculture
Bromodeoxyuridine
DNA
Female
Genotype
Glutathione Transferase
Humans
Italy
Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Micronuclei, Chromosome-Defective

Micronucleus Tests

Microscopy, Fluorescence

Multivariate Analysis

Occupational Exposure

Source

Open in PubMed

Identifiers

PMID: 10333536
DOI: 10.1016/s1383-5718(99)00051-0

Genes

GSTM1
NAT2
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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