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Article

Anticipation of onset age in familial Parkinson's disease without SCA gene mutations.

Parkinsonism & related disorders - 1 Jun 2006

Huang Yue, Hayes Michael, Harding Antony J, Brooks William S, Fung Victor S C, Rowe Dominic, Joffe Ron, Crimmins Denis, Hely Mariese, Halliday Glenda M

Abstract excerpt

Assessment of a series of 279 cases with Lewy body disease revealed 14 families having a family history consistent with autosomal dominant inheritance, eight of these with dominant Parkinsonism and six with dominant dementia. Analysis of the age at onset and genetic features in these families revealed significant anticipation only in a subset of parkinsonian families, with no pathological alleles for...

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Identifiers

PMID: 16621662
DOI: 10.1016/j.parkreldis.2006.01.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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