Article
RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase.
Nature - 4 Apr 1996
Polson A G, Bass B L, Casey J L
Abstract excerpt
Hepatitis delta virus (HDV) is a subviral human pathogen that requires hepatitis B virus (HBV) for packaging. Concurrent infection by HBV and HDV increases the risk of severe liver disease compared to infection with HBV alone. The HDV genome is a closed circular RNA of about 1,700 bases which is replicated through an RNA intermediate, the antigenome. Both RNAs can be folded into highly base-paired, rod-shaped...
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