Beyond hepatitis D virus: the discovery of animal deltaviruses, their diversity, helpers and their position in an expanding world of circular RNA replicons.

Abstract excerpt

Hepatitis D virus (HDV) was long considered a singular human satellite virus that depends on hepatitis B virus (HBV) for envelopment and transmission. Recent metatranscriptomic mining has uncovered a growing diversity of HDV-like viruses, we term deltaviruses, across vertebrates, invertebrates, and environmental samples, overturning assumptions about strict hepatic tropism and obligatory hepadnavirus helpers....

Topics

• Animals
• Hepatitis Delta Virus
• Humans
• RNA, Circular
• Replicon
• Helper Viruses
• Virus Replication
• Hepatitis D
• RNA, Viral
• RNA Replication
• Genetic Variation