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Host RNA circles and the origin of hepatitis delta virus

1 Jan 2014

Abstract excerpt

Recent reports show that many cellular RNAs are processed to form circular species that are relatively abundant and resistant to host nucleases. In some cases, such circles actually bind host microRNAs. Such depletion of available microRNAs appears to have biological roles; for instance, in homeostasis and disease. These findings regarding host RNA circles support a speculative reappraisal of the origin and mode...

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PMID: 24659888
DOI: 10.3748/wjg.v20.i11.2971

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