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Article

Illegitimate replication of linear hepadnavirus DNA through nonhomologous recombination.

Journal of virology - 1 Jul 1995

Yang W, Summers J

Abstract excerpt

Linear hepadnavirus DNA in primary hepatocyte cultures efficiently participates in intra- and intermolecular nonhomologous recombination at its ends. The products of this recombination are (i) monomeric covalently closed circular DNAs (cccDNAs) with deletions and insertions around the site of joi...

Topics

Animals
Base Sequence
Cells, Cultured
DNA Replication
DNA, Circular
Ducks
Hepadnaviridae
Liver
Molecular Sequence Data
Mutation
Recombination, Genetic
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7769660
DOI: 10.1128/JVI.69.7.4029-4036.1995
PMCID: PMC189136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7769660-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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