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Article

Illegitimate replication of linear hepadnavirus DNA through nonhomologous recombination.

Journal of virology - 1 Jul 1995

Yang W, Summers J

Abstract excerpt

Linear hepadnavirus DNA in primary hepatocyte cultures efficiently participates in intra- and intermolecular nonhomologous recombination at its ends. The products of this recombination are (i) monomeric covalently closed circular DNAs (cccDNAs) with deletions and insertions around the site of joining and (ii) oligomeric forms in which monomers are joined near the ends in random orientation. A fraction of...

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Identifiers

PMID: 7769660
DOI: 10.1128/JVI.69.7.4029-4036.1995
PMCID: PMC189136

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Source receipt: pubmed, retrieved 7 Sept 2026.

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