Article
Unbranched rod-like RNA is required for RNA editing of hepatitis delta virus genotype 2 and genotype 4.
Virus research - 1 Dec 2023
Hsu Chao-Wei, Hsu Hsueh-Ying, Chen Chien-Hung, Chao Mei
Abstract excerpt
RNA editing of the hepatitis delta virus (HDV) is essential for generating the large delta antigen, which is crucial for virion assembly. In HDV genotype 1 (HDV-1), editing occurs within the context of the unbranched rod-like structure characteristic of HDV RNA, while RNA editing in HDV-3 requires a branched double-hairpin structure. The regulation of RNA editing in HDV-2 and HDV-4 remains uncertain. Based on...
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