Article
Association of SULT2A1 allelic variants with plasma adrenal androgens and prostate cancer in African American men.
The Journal of steroid biochemistry and molecular biology - 1 Jun 2006
Wilborn Teresa W, Lang Nicholas P, Smith Michelle, Meleth Sreelatha, Falany Charles N
Abstract excerpt
Dehydroepiandrosterone (DHEA) sulfate which is present at micromolar levels in the plasma, can be desulfated to supply free DHEA for metabolism to androgens or estrogens in peripheral tissues. Human cytosolic sulfotransferase (SULT) 2A1 catalyzes DHEA sulfation in the adrenal cortex. Three SULT2A...
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