Article
Toll-like receptor 4 Asp299Gly/Thr399Ile polymorphisms are a risk factor for Candida bloodstream infection.
European cytokine network - 1 Mar 2006
Van der Graaf Chantal A A, Netea Mihai G, Morré Servaas A, Den Heijer Martin, Verweij Paul E, Van der Meer Jos W M, Kullberg Bart Jan
Abstract excerpt
Toll-like receptor (TLR)-4 is an important pattern recognition receptor for Candida albicans, playing a role in innate host defense. We investigated whether there is an association between the TLR4 Asp299Gly or TLR4 Thr399Ile polymorphism, and the occurrence of Candida bloodstream infection. We performed a case-control study, involving 43 patients with a Candida bloodstream infection and 166 healthy individuals....
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