Article
Role of truncating mutations in MME gene in fetomaternal alloimmunisation and antenatal glomerulopathies.
Lancet (London, England) - 1 Jan 2000
Debiec Hanna, Nauta Jeroen, Coulet Florence, van der Burg Mirjam, Guigonis Vincent, Schurmans Thierry, de Heer Emile, Soubrier Florent, Janssen Francoise, Ronco Pierre
Abstract excerpt
BACKGROUND: Membranous glomerulonephritis is an immune-mediated disease. In a recent case of antenatal membranous glomerulonephritis, we identified neutral endopeptidase (NEP) as the podocyte target antigen of circulating antibodies produced by the mother who failed to express NEP on granulocytes...
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