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Article

Non-coding RNAs, guardians of the p53 galaxy.

Seminars in cancer biology - 1 Oct 2021

Chen Song, Thorne Rick F, Zhang Xu Dong, Wu Mian, Liu Lianxin

Abstract excerpt

The TP53 gene is arguably the most important tumor suppressor gene known, contributing multifaceted roles to the process of tumor development. Its protein product p53, is a crucial sequence-specific transcription factor which regulates the expression of a large network of protein-coding genes, as well as thousands of noncoding RNAs (ncRNAs), notably microRNAs and long ncRNAs (lncRNAs). Through a variety of direct...

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Identifiers

PMID: 32927018
DOI: 10.1016/j.semcancer.2020.09.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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