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Article

Evolution of hormone-receptor complexity by molecular exploitation.

Science (New York, N.Y.) - 7 Apr 2006

Bridgham Jamie T, Carroll Sean M, Thornton Joseph W

Abstract excerpt

According to Darwinian theory, complexity evolves by a stepwise process of elaboration and optimization under natural selection. Biological systems composed of tightly integrated parts seem to challenge this view, because it is not obvious how any element's function can be selected for unless the partners with which it interacts are already present. Here we demonstrate how an integrated molecular system-the...

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PMID: 16601189
DOI: 10.1126/science.1123348

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