Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late <i>Drosophila melanogaster</i> oogenesis

Abstract excerpt

Autophagy is an evolutionarily conserved pathway responsible for degradation of cytoplasmic material via the lysosome. Although autophagy has been reported to contribute to cell death, the underlying mechanisms remain largely unknown. In this study, we show that autophagy controls DNA fragmentation during late oogenesis in Drosophila melanogaster. Inhibition of autophagy by genetically removing the function of...

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