Article
Drosophila as a model to understand autophagy deregulation in human disorders.
Progress in molecular biology and translational science - 1 Jan 2020
Denton Donna, O'Keefe Louise, Kumar Sharad
Abstract excerpt
Autophagy has important functions in normal physiology to maintain homeostasis and protect against cellular stresses by the removal of harmful cargos such as dysfunctional organelles, protein aggregates and invading pathogens. The deregulation of autophagy is a hallmark of many diseases and therapeutic targeting of autophagy is highly topical. With the complex role of autophagy in disease it is essential to...
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