Article
Genetic detoxification and adjuvant-activity retention of Escherichia coli enterotoxin LT.
Avian pathology : journal of the W.V.P.A - 1 Apr 2006
Vasserman Yelena, Pitcovski Jacob
Abstract excerpt
Intensive effort has been invested in the search for new effective vaccines that can be conveniently administered, with minimal handling of birds. Heat-labile enterotoxin (LT) of Escherichia coli H10407 is known as a powerful adjuvant for injection and oral administration. However, to use the toxin as an immunostimulator in animals, its toxicity must be neutralized. To this aim, we modified the LT gene by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
