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Article

Genomic structure of the human prototype strain H of hepatitis C virus: comparison with American and Japanese isolates.

Proceedings of the National Academy of Sciences of the United States of America - 15 Nov 1991

Inchauspe G, Zebedee S, Lee D H, Sugitani M, Nasoff M, Prince A M

Abstract excerpt

Genomic RNA from the human prototype strain H of the hepatitis C virus (HCV-H) has been molecularly cloned and sequenced. The HCV-H sequence reported consists of 9416 nucleotides including the 5' and 3' untranslated regions. HCV-H shows 96% amino acid identity with the American isolate HCV-1 but only 84.9% with the Japanese isolates HCV-J and HCV-BK. In addition to the hypervariable region (region V) previously...

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Identifiers

PMID: 1658800
DOI: 10.1073/pnas.88.22.10292
PMCID: PMC52914

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