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Perilipin gene variation determines higher susceptibility to insulin resistance in Asian women when consuming a high-saturated fat, low-carbohydrate diet.

Diabetes care - 1 Jun 2006

Corella Dolores, Qi Lu, Tai E Shyong, Deurenberg-Yap Mabel, Tan Chee Eng, Chew Suok Kai, Ordovas Jose M

Abstract excerpt

OBJECTIVE: To investigate the association between genetic variation in the adipocyte protein perilipin (PLIN) and insulin resistance in an Asian population as well as to examine their modulation by macronutrient intake. RESEARCH DESIGN AND METHODS: A nationally representative sample (Chinese, Malays, and Indians) was selected in the Singapore National Health Survey following the World Health...

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PMID: 16732014
DOI: 10.2337/dc06-0045

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Perilipin gene variation determines higher susceptibility to insulin resistance in Asian women when consuming a high-saturated fat, low-carbohydrate diet.PMID 16732014Read ↗

Perilipin polymorphism interacts with saturated fat and carbohydrates to modulate insulin resistance.Semantic proximity Read ↗

Perilipin polymorphism interacts with dietary carbohydrates to modulate anthropometric traits in hispanics of Caribbean origin.Semantic proximity Read ↗

Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population.Semantic proximity Read ↗

Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss.Semantic proximity Read ↗

Postprandial triacylglycerol metabolism is modified by the presence of genetic variation at the perilipin (PLIN) locus in 2 white populations.Semantic proximity Read ↗

Association between three genetic variants of the Perilipin Gene (PLIN) and glucose metabolism: results from a replication study among Chinese adults and a meta-analysis.Semantic proximity Read ↗

Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women.Semantic proximity Read ↗

Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women.Semantic proximity Read ↗

Polymorphism PLIN1 11482 G>A interacts with dietary intake to modulate anthropometric measures and lipid profile in adults with normal-weight obesity syndrome.Semantic proximity Read ↗

Gender-specific association of a perilipin gene haplotype with obesity risk in a white population.Semantic proximity Read ↗

High fat diet modifies the association of lipoprotein lipase gene polymorphism with high density lipoprotein cholesterol in an Asian Indian populationSemantic proximity Read ↗

Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes.Semantic proximity Read ↗

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