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Article

Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Sept 2008

Bergmann A, Li J, Reimann M, Hentrich T, Hanefeld M, Bornstein S R, Schwarz P E H

Abstract excerpt

Perilipins are hormonally regulated phosphorylated proteins that coat the intracellular lipid storage droplet . They are essential for the regulation of triglyceride deposition and mobilization . The human perilipin gene (PLIN) is located to 15q26.1, near the susceptibility loci for obesity, and insulin-dependent diabetes mellitus, and hypertriglyceridemia. Therefore, it is considered as a candidate gene for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18777456
DOI: 10.1055/s-2008-1081493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes.PMID 18777456Read ↗

Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women.Semantic proximity Read ↗

Study of the impact of perilipin polymorphisms in a French population.Semantic proximity Read ↗

Perilipin polymorphisms are risk factors for the development of obesity in adolescents? A case-control study.Semantic proximity Read ↗

Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population.Semantic proximity Read ↗

A functional variant in the exon 5 of PLIN1 reduces risk of central obesity by possible regulation of lipid storage.Semantic proximity Read ↗

Gender-specific association of a perilipin gene haplotype with obesity risk in a white population.Semantic proximity Read ↗

Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome.Semantic proximity Read ↗

Association between three genetic variants of the Perilipin Gene (PLIN) and glucose metabolism: results from a replication study among Chinese adults and a meta-analysis.Semantic proximity Read ↗

Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss.Semantic proximity Read ↗

Perilipin 1: a systematic review on its functions on lipid metabolism and atherosclerosis in mice and humans.Semantic proximity Read ↗

Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women.Semantic proximity Read ↗

Perilipin Deficiency and Autosomal Dominant Partial LipodystrophySemantic proximity Read ↗

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