Genomic Profiling Identifies Discrete Deletions Associated with Translocations in Glioblastoma Multiforme

Abstract excerpt

Glioblastoma multiforme is the most common tumor arising in the central nervous system. Patients with these tumors have limited treatment options and their disease is invariably fatal. Molecularly targeted agents offer the potential to improve patient treatment, however the use of these will require a fuller understanding of the genetic changes in these complex tumors. In this study, we identify copy number...

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