Article
Zebrafish fat-free is required for intestinal lipid absorption and Golgi apparatus structure.
Cell metabolism - 1 Apr 2006
Ho Shiu-Ying, Lorent Kristin, Pack Michael, Farber Steven A
Abstract excerpt
The zebrafish fat-free (ffr) mutation was identified in a physiological screen for genes that regulate lipid metabolism. ffr mutant larvae are morphologically indistinguishable from wild-type sibling larvae, but their absorption of fluorescent lipids is severely impaired. Through positional cloning, we have identified a causative mutation in a highly conserved and ubiquitously expressed gene within the ffr locus....
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