Article
Genetic analysis of digestive physiology using fluorescent phospholipid reporters.
Science (New York, N.Y.) - 18 May 2001
Farber S A, Pack M, Ho S Y, Johnson I D, Wagner D S, Dosch R, Mullins M C, Hendrickson H S, Hendrickson E K, Halpern M E
Abstract excerpt
Zebrafish are a valuable model for mammalian lipid metabolism; larvae process lipids similarly through the intestine and hepatobiliary system and respond to drugs that block cholesterol synthesis in humans. After ingestion of fluorescently quenched phospholipids, endogenous lipase activity and ra...
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