Article
A case of scrapie in a sheep carrying the lysine-171 allele of the prion protein gene.
Archives of virology - 1 Sept 2006
Acutis P L, Martucci F, Mazza M, Peletto S, Iulini B, Corona C, Bozzetta E, Casalone C, Caramelli M
Abstract excerpt
Susceptibility to scrapie in sheep depends on the host PrP genotype. No data about the linkage of the rare ARK allele to differential scrapie susceptibility are currently available. Several tissues isolated from sheep from an Italian scrapie outbreak and carrying the ARK allele were examined for the presence of the pathological prion protein. A weak positivity was detected only by Western blot in the brainstem of...
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