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Article

RS5444, a novel PPARgamma agonist, regulates aspects of the differentiated phenotype in nontransformed intestinal epithelial cells.

Molecular and cellular endocrinology - 7 Jun 2006

Chen Lu, Bush Craig R, Necela Brian M, Su Weidong, Yanagisawa Masahiro, Anastasiadis Panos Z, Fields Alan P, Thompson E Aubrey

Abstract excerpt

Peroxisome proliferator-activated receptor-gamma (PPARgamma) is expressed in the intestinal epithelium, yet little is known about the physiological role of PPARgamma in the small bowel or the effects of PPARgamma on small intestinal epithelial cells. The present studies investigate cellular and genomic effects of PPARgamma in nontransformed rat intestinal epithelial cells (RIE). These cells were engineered to...

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Identifiers

PMID: 16574311
DOI: 10.1016/j.mce.2006.02.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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