Article
Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice.
Endocrinology - 1 Aug 2007
Schaiff W Timothy, Knapp F F Russ, Barak Yaacov, Biron-Shental Tal, Nelson D Michael, Sadovsky Yoel
Abstract excerpt
The nuclear receptor peroxisome proliferator activated receptor gamma (PPARgamma) is essential for murine placental development. We previously showed that activation of PPARgamma in primary human trophoblasts enhances the uptake of fatty acids and alters the expression of several proteins associated with fatty acid trafficking. In this study we examined the effect of ligand-activated PPARgamma on placental...
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