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Article

Arg16 homozygosity of the beta2-adrenergic receptor improves the outcome after beta2-agonist tocolysis for preterm labor.

Clinical pharmacology and therapeutics - 1 Dec 2005

Landau Ruth, Morales Michel A, Antonarakis Stylianos E, Blouin Jean-Louis, Smiley Richard M

Abstract excerpt

BACKGROUND: Beta(2)-adrenergic receptor (beta(2)AR) agonists are not consistently successful when administered as tocolytic therapy. The beta(2)AR displays genetic variability; an arginine-to-glycine substitution at codon 16 (Arg16Gly) has been shown to increase receptor desensitization in respon...

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Share to Adrenergic beta-2 Receptor Agonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant, Low Birth Weight

Share to Obstetric Labor, Premature

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Share to Receptors, Adrenergic, beta-2

Share to Respiratory Distress Syndrome, Newborn

Source

Identifiers

PMID: 16338281
DOI: 10.1016/j.clpt.2005.08.021

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16338281-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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