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Article

G-2548A polymorphism of the leptin gene is correlated with extreme obesity in Taiwanese aborigines.

Obesity (Silver Spring, Md.) - 1 Feb 2006

Wang Tsu-Nai, Huang Meng-Chuan, Chang Wen-Tsan, Ko Albert Min-Shan, Tsai Eing-Mei, Liu Chih-Shan, Lee Chien-Hung, Ko Ying-Chin

Abstract excerpt

We examined the genetic associations of the G-2548A polymorphism in the promoter of the leptin (LEP) gene and the Gln223Arg (Q223R) polymorphism of the leptin receptor (LEPR) gene with obesity. Two hundred twenty-six obese aboriginal subjects (BMI > or = 27 kg/m2) and 182 aboriginal subjects with normal weight (BMI < 25 kg/m2) participated in this study. The polymorphisms of LEP G-2548A and LEPR Q223R were...

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Source

Identifiers

PMID: 16571841
DOI: 10.1038/oby.2006.23

Genes

LEP
LEPR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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