The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders.

doi:10.1007/s00439-009-0768-9

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders.

Human genetics - 1 Mar 2010

Furusawa Takuro, Naka Izumi, Yamauchi Taro, Natsuhara Kazumi, Kimura Ryosuke, Nakazawa Minato, Ishida Takafumi, Inaoka Tsukasa, Matsumura Yasuhiro, Ataka Yuji, Nishida Nao, Tsuchiya Naoyuki, Ohtsuka Ryutaro, Ohashi Jun

Abstract excerpt

Various Pacific Island populations have experienced a marked increase in the prevalence of obesity in past decades. This study examined the association of a promoter polymorphism of the leptin gene (LEP), G-2548A (rs7799039), and two non-synonymous single nucleotide polymorphisms of the leptin re...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Arginine

Share to Genetic Linkage

Share to Glutamic Acid

Share to Obesity

Share to Pacific Islands

Share to Prevalence

Share to Receptors, Leptin

Source

Open in PubMed

Identifiers

PMID: 20183928
DOI: 10.1007/s00439-009-0768-9

Genes

LEPR
LEP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20183928-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders.PMID 20183928Read ↗

Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans.Semantic proximity Read ↗

p.Q223R leptin receptor polymorphism associated with obesity in Brazilian multiethnic subjects.Semantic proximity Read ↗

LEPR p.Q223R Polymorphism influences plasma leptin levels and body mass index in Tunisian obese patients.Semantic proximity Read ↗

Relationship Between Leptin G2548A and Leptin Receptor Q223R Gene Polymorphisms and Obesity and Metabolic Syndrome Risk in Tunisian VolunteersSemantic proximity Read ↗

Variations in the Obesity Gene "LEPR" Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis.Semantic proximity Read ↗

G-2548A polymorphism of the leptin gene is correlated with extreme obesity in Taiwanese aborigines.Semantic proximity Read ↗

LEPR p.Q223R, beta3-AR p.W64R and LEP c.-2548G>A gene variants in obese Brazilian subjects.Semantic proximity Read ↗

Association of LEPR Gln223Arg Polymorphism with Obstructive Sleep Apnea Syndrome: A Meta-Analysis.Semantic proximity Read ↗

[Meta-analysis on the relationship between leptin receptor Gln223Arg and Pro1019Pro gene polymorphism and obesity in the Chinese population].Semantic proximity Read ↗

Association of leptin receptor gene Q223R polymorphism on lipid profiles in comparison study between obese and non-obese subjects.Semantic proximity Read ↗

Association between variants of the leptin receptor gene (LEPR) and overweight: a systematic review and an analysis of the CoLaus study.Semantic proximity Read ↗

A meta-analysis of associations of LEPR Q223R and K109R polymorphisms with Type 2 diabetes risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.