Article
Modifier genes and sickle cell anemia.
Current opinion in hematology - 1 May 2006
Steinberg Martin H, Adewoye Adeboye H
Abstract excerpt
PURPOSE OF REVIEW: With the completion of the human genome project and HapMap, previously unknown genetic polymorphisms associated with disease have been observed. This review highlights genetic polymorphisms that have provided insight into the pathophysiology underlying the many phenotypes of sickle cell disease. RECENT FINDINGS: The phenotypes of sickle cell disease are likely to be modulated by polymorphisms...
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