Article
Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic whites and blacks: the HERITAGE Family Study.
Diabetologia - 1 Jun 2005
An P, Teran-Garcia M, Rice T, Rankinen T, Weisnagel S J, Bergman R N, Boston R C, Mandel S, Stefanovski D, Leon A S, Skinner J S, Rao D C, Bouchard C
Abstract excerpt
AIMS/HYPOTHESIS: Impaired insulin secretion, insulin action, insulin-independent glucose effectiveness, glucose tolerance and the associated abnormalities in insulin and glucose metabolism phenotypes are precursors of type 2 diabetes. Genome-wide multipoint variance component linkage scans were carried out using 654 markers to identify quantitative trait loci for insulin sensitivity, acute insulin response to...
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