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Article

Hemoglobin Q-Thailand related disorders: origin, molecular, hematological and diagnostic aspects.

Blood cells, molecules & diseases - 15 Oct 2010

Singsanan Sanita, Karnpean Rossarin, Fucharoen Goonnapa, Sanchaisuriya Kanokwan, Sae-Ung Nattaya, Fucharoen Supan

Abstract excerpt

We describe the molecular and hematological profiles of thalassemia syndromes caused by interactions of hemoglobin (Hb) Q-Thailand [α74(EF3) Asp-His] and various hemoglobinopathies found in 52 unrelated adult Thai subjects. Ten genotypes including several previously undescribed conditions were observed, which were classified into 4 groups. Group I included 26 Hb Q-Thailand heterozygotes and a homozygotous...

Topics

Adult
Alleles
Electrophoresis, Capillary
Female
Hemoglobin E
Hemoglobin H
Hemoglobins, Abnormal
Heterozygote
Homozygote
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

alpha-Thalassemia

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PMID: 20615730
DOI: 10.1016/j.bcmd.2010.06.001

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